Gastrointestinal Peptide Hormones and Breast Cancer

Functions of Obesity-related Hormones in Breast Cancer: A Review

ABSTRACT            Obesity is a health problem defined as abnormal or excessive fat accumulation in adipose tissue. Adipokines such as adiponectin, visfatin and resistin are bioactive polypeptides with pro- and anti-inflammatory properties that are secreted by the adipose tissue that are involved in the pathogenesis and prognosis of diseases ...

Hormones and breast cancer: what's the story?

It has now been 30 years since the first epidemiologic report linked menopausal estrogen therapy—the exogenous estrogens that, along with progestins, came to be known as ‘‘hormone replacement therapy’’—with an increased risk of breast cancer (1). Today, the body of evidence on this association is substantial and, perhaps, unique. This includes a pooled analysis published in 1997 by the Collabor...

Breast Implants and Breast Cancer

Gastrointestinal Hormones: Introduction and Index

New Hormones for Advanced Breast Cancer.

The beginnings of endocrine therapy for breast cancer can be traced to British surgeon George Beatson. In 1896, he described a young women with lo cally recurrent breast cancer who responded to oophorectomy. Today, several endocrine therapies are available, including selective estrogen receptor modulators (tamoxifen and others), aromatase inhibitors, progestins, androgens, and LHRH agonists. Ap...